دانلود Persistent impairment in working memory following severe hyperglycemia in newly diagnosed type 2 diabetes

ترجمه Persistent impairment in working memory following severe hyperglycemia in newly diagnosed type 2 diabetes
قیمت : 210,000 ریال
شناسه محصول : 2008276
نویسنده/ناشر/نام مجله : Endocrinology, diabetes & metabolism case reports
سال انتشار: 2017
تعداد صفحات انگليسي : 4
نوع فایل های ضمیمه : Pdf+Word
حجم فایل : 183 Kb
کلمه عبور همه فایلها : www.daneshgahi.com
عنوان انگليسي : Persistent impairment in working memory following severe hyperglycemia in newly diagnosed type 2 diabetes

چکیده

Abstract

Acute hyperglycemia has been shown to cause cognitive impairments in animal models. There is growing appreciation of the numerous effects of hyperglycemia on neuronal function as well as blood–brain barrier function. In humans, hypoglycemia is well known to cause cognitive deficits acutely, but hyperglycemia has been less well studied. We present a case of selective neurocognitive deficits in the setting of acute hyperglycemia. A 60-year-old man was admitted to the hospital for an episode of acute hyperglycemia in the setting of newly diagnosed diabetes mellitus precipitated by steroid use. He was managed with insulin therapy and discharged home, and later, presented with complaints of memory impairment. Deficits included impairment in his declarative and working memory, to the point of significant impairment in his overall functioning. The patient had no structural lesions on MRI imaging of the brain or other systemic illnesses to explain his specific deficits. We suggest that his acute hyperglycemia may have caused neurological injury, and may be responsible for our patient’s memory complaints.

Keywords: type 2 diabetes
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