دانلود Genetics of Male Infertility
عنوان انگليسي
:
Genetics of Male Infertility
چکیده
Abstract
· Much of idiopathic male infertility is likely to have a genetic cause.
· Men who have nonobstructive azoospermia or severe oligospermia with total motile count less than5 million should have a karyotype and Y chromosome microdeletion.
· Klinefelter syndrome (47,XXY) is the most common chromosomal abnormality with a frequency of 1:600 males and has a wide spectrum of clinical presentation.
· Men with an AZFa, AZFb, AZFb/c microdeletion uniformly have complete absence of spermatogenesis.
· If a male has congenital bilateral absence of the vas deferens, it is critical to offer him and his partner genetic testing for cystic fibrosis mutations as well as genetic counseling
Keywords:
Migraine Testosterone Oestradiol Cataract Nash
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