دانلود Gold nanoparticle probes for the detection of nucleic acid targets

ترجمه مقالهGold nanoparticle probes for the detection of nucleic acid targets
قیمت : 1,060,000 ریال
شناسه محصول : 2007941
نویسنده/ناشر/نام مجله : Clinica Chimica Acta
سال انتشار: 2006
تعداد صفحات انگليسي : 7
نوع فایل های ضمیمه : PdF+Word
حجم فایل : 399 Kb
کلمه عبور همه فایلها : www.daneshgahi.com
عنوان انگليسي : Gold nanoparticle probes for the detection of nucleic acid targets

چکیده

Abstract

Background: Advances in nanoscience are having a significant impact on many scientific fields and are resulting in the development of a variety of important technologies. This impact is particularly large in the field of biodiagnostics, where a number of nanoparticle-based assays have been introduced for biomolecular detection, with DNA- or protein-functionalized gold nanoparticles used as the target-specific probes.

Methods: Assays provide an analysis of the unique biophysical properties displayed by gold nanoparticles and have advantages over conventional detection methods (e.g., molecular fluorophores, real-time polymerase chain reaction, RT-PCR, enzyme linked immunosorbent assays, ELISAs, gel electrophoresis, and microarray technologies).

Conclusion: Some of the advantages include the assays’ PCR-like sensitivity, their selectivity for target sequences, their capacity for massive multiplexing, their time efficiency, and most importantly, their ability to be performed at the point of care.D2005 Elsevier B.V. All rights reserved.

Keywords: Bio-barcode assay Gold nanoparticles Microarray Scanometric detection Oligonucleotides
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