دانلود Magnetic nanoparticles for local drug delivery using magnetic implants
عنوان انگليسي
:
Magnetic nanoparticles for local drug delivery using magnetic implants
چکیده
Abstract
Magnetic nanoparticles are good candidates used for the targeted delivery of anti-tumor agents. They can be concentrated on a desired region, reducing collateral effects and improving the efficiency of the chemotherapy. We propose a method in which permanent magnets are implanted by laparoscopic technique directly in the affected organ. This method proposes the use of Fe@C nanoparticles, which are loaded with doxorubicin and injected intravenously. The particles, once attracted to the magnet, release the drug at the tumor region. This method seems to be more promising and effective than that based on the application of external magnetic fields.
Keywords:
Magnetic nanoparticle Magnetic implant Biocompatibility Local therapy Drug delivery
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