دانلود ?Can Mitochondria DNA Provide a Novel Biomarker for Evaluating the Risk and Prognosis of Colorectal Cancer

ترجمه فارسی Can Mitochondria DNA Provide a Novel Biomarker for Evaluating the Risk and Prognosis of Colorectal Cancer
قیمت : 230,000 ریال
شناسه محصول : 2009276
نویسنده/ناشر/نام مجله : Disease markers
سال انتشار: 2017
تعداد صفحات انگليسي : 9
نوع فایل های ضمیمه : pdf+word
حجم فایل : 709 Kb
کلمه عبور همه فایلها : www.daneshgahi.com
عنوان انگليسي : ?Can Mitochondria DNA Provide a Novel Biomarker for Evaluating the Risk and Prognosis of Colorectal Cancer

چکیده

Abstract

Colorectal cancer (CRC) was one of the most frequent cancers worldwide. Accurate risk and prognosis evaluation could obtain better quality of life and longer survival time for the patients. Current research hotspot was focus on the gene biomarker to evaluate the risk and prognosis. Mitochondrion contains its own DNA and regulates self-replicating so that it can be as a candidate biomarker for evaluating the risk and prognosis of colorectal cancer. But there were already huge controversies on this issue. The review was to summarize current viewpoints of the controversial issues and described our understanding from the four aspects including mtDNA copy number, mitochondrial displacement loop, mtDNA variation, and mtDNA microsatellite instability, wishing the summary of the mtDNA in colorectal cancer could provide a meaningful reference or a valuable direction in the future studies.

Keywords: Colorectal Cancer
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