دانلود Effects of a Chitosan Coating on Properties of Retinol- Encapsulated Zein Nanoparticles
عنوان انگليسي
:
Effects of a Chitosan Coating on Properties of Retinol- Encapsulated Zein Nanoparticles
چکیده
Abstract
Zein nanoparticles coated with chitosan were prepared for encapsulation of retinol. The mean particle size of retinol-loaded zein nanoparticles was approximately 300 nm. After coating with chiotsan, the mean particle size increased to >500 nm. The zeta potential of retinol-loaded zein nanoparticles was approximately -30 mV, which was changed to >+24 mV after chitosan coating. The encapsulation efficiency of zein nanoparticles increased from 64.9% to >80% after chitosan coating. The release profile was greatly improved with a chitosan coating, and a slow release rate was observed. FTIR analysis of retinol-loaded chitosan-coated zein nanoaprticles showed cross-linking between zein and retinol through electrostatic interactions. Photochemical stability against UV light was greatly improved to >90% after encapsulation. The concentration of chitosan, the Mw of chitosan, and the zein/chitosan volume ratio were important parameters affecting the properties of nanoparticles.
Keywords:
retinol zein chitosan nanoparticle encapsulation
سایر منابع شيمی در زمینه نانوذرات